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KMID : 1011220150020010004
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Clinical & Experimental Thrombosis and Hemostasis
2015 Volume.2 No. 1 p.4 ~ p.7
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Incidence of Chronic Thromboembolic Pulmonary Hypertension after Pulmonary Embolism: A Retrospective Analysis in a University Teaching Hospital
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Choi Won-Il
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Abstract
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Purpose: Chronic thromboembolic pulmonary hypertension (CTEPH) is associated with considerable morbidity and mortality. Its incidence after pulmonary embolism and associated risk factors in the Korean population are not well documented.
Methods: A retrospective cohort study was conducted to assess the incidence of symptomatic CTEPH in patients with an acute episode of pulmonary embolism without prior history of venous thromboembolism. Patients experiencing unexplained persistent dyspnea during follow-up underwent transthoracic echocardiography, ventilation?perfusion lung scanning and computed tomography (CT) pulmonary angiography. CTEPH was considered to be present if estimated systolic pulmonary-artery pressure exceeded 40 mm Hg with evidence of thromboembolism on either ventilation-perfusion scanning or CT pulmonary angiography.
Results: The cumulative incidence of symptomatic CTEPH was 1.9 percent at six months, 3.2 percent at one year, and 3.9 percent at three years. One case of recurrence after three years was noted among the patients with more than three years of follow-up data.
Conclusion: CTEPH is a not uncommon disease and suggests the need for careful evaluation of pulmonary embolism during follow-up.
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KEYWORD
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Incidence, Pulmonary Embolism, Pulmonary Hypertension
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